Cancer is a leading cause of death worldwide, but thanks to advances in medical research, there are now more effective anti-cancer medicines available than ever before. Here is a list of the top 10 anti-cancer medicines in 2023, based on their sales and efficacy:

1. Opdivo (nivolumab): Opdivo is an immunotherapy drug that works by helping the body’s own immune system fight cancer cells. It is approved for the treatment of a wide range of cancers, including melanoma, lung cancer, kidney cancer, and colorectal cancer.
2. Keytruda (pembrolizumab): Keytruda is another immunotherapy drug that works in a similar way to Opdivo. It is also approved for the treatment of a wide range of cancers.
3. Imbruvica (ibrutinib): Imbruvica is a targeted therapy drug that is used to treat B-cell malignancies, such as chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL).
4. Darzalex (daratumumab): Darzalex is another targeted therapy drug that is used to treat B-cell malignancies. It is particularly effective against multiple myeloma.
5. Ibrance (palbociclib): Ibrance is a targeted therapy drug that is used to treat breast cancer. It is particularly effective against advanced and metastatic breast cancer.
6. Tagrisso (osimertinib): Tagrisso is a targeted therapy drug that is used to treat lung cancer. It is particularly effective against lung cancer that has the EGFR mutation.
7. Lynparza (olaparib): Lynparza is a targeted therapy drug that is used to treat ovarian cancer, breast cancer, and pancreatic cancer. It is particularly effective against cancers that have BRCA mutations.
8. Trodelvy (sacituzumab govitecan): Trodelvy is a targeted therapy drug that is used to treat triple-negative breast cancer. It is a type of antibody-drug conjugate (ADC), which means that it combines an antibody with a chemotherapy drug.
9. Glofitamab (TNB383B): Glofitamab is a bispecific antibody that is used to treat relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It works by binding to two different proteins on the surface of cancer cells, which triggers the immune system to kill them.
10. Epcoritamab (DuoBody-CDh19): Epcoritamab is another bispecific antibody that is used to treat DLBCL. It works in a similar way to Glofitamab.

These are just a few of the many anti-cancer medicines that are available today. The best medicine for you will depend on the type of cancer you have, the stage of the cancer, and your overall health. If you have been diagnosed with cancer, it is important to talk to your doctor about the best treatment options for you.

It is important to note that this list is not exhaustive, and there are many other effective anti-cancer medicines available. Additionally, new anti-cancer medicines are being developed all the time, so it is important to stay up-to-date on the latest research.